Spot size and pulse duration dependence of laser-induced damage. Laser-induced electric breakdown in solids. These findings suggest optimal laser parameters for corneal surgery. At pulse widths less than 10 ps and with fluences near the breakdown threshold, ablations are maximally precise and efficient. Corneal tissue examined histologically showed similar fluence dependency.ĬONCLUSIONS: Corneal tissue photodisruption thresholds demonstrate pulse width dependence. Breakdown for pulse widths below 10 ps showed little intershot variability, resulting in highly reproducible fluence thresholds. RESULTS: Corneal breakdown thresholds decreased at a faster rate from 7 ns to approximately 10 picoseconds (ps), compared to further reductions in pulse width below 10 ps, where little variation was seen. Using multiple shots, the photodisruption threshold and cutting depth at each pulse width were determined histologically. The laserinduced breakdown fluence threshold at each pulse width was determined by monitoring individual plasma emissions. METHODS: A laser system that delivers a wide range of pulse energies and pulse widths was used to produce ablations at pulse widths from 100 femtoseconds (fs) to 7 nanoseconds (ns). BACKGROUND: We investigated the role of laser pulse width in determining fluence thresholds and efficiency for corneal photodisruption.
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